Challenges in synergy between radiation and immunotherapy
10.3760/cma.j.issn.1004-4221.2017.10.025
- VernacularTitle:放疗与免疫治疗协同作用的研究进展
- Author:
Xiling ZHU
1
;
Gong LI
Author Information
1. 武警总医院肿瘤二科
- Keywords:
Neoplasms/radiotherapy;
Neoplasms/immunotherapy;
Research progress
- From:
Chinese Journal of Radiation Oncology
2017;26(10):1227-1230
- CountryChina
- Language:Chinese
-
Abstract:
Radiotherapy ( RT) is used as primary treatment for numerous cancers. Although it is usually described as an immunosuppressive modality,there are new preclinical evidences suggesting that RT could have also generated substantial changes in the tumor microenvironment, including triggering an inflammatory process. Some studies established the proof of concept that combining RT with strategies modifying immunology could enhance antitumor effects.