Assessment of pressure-volume loop in patients with pulmonary hypertension and the correlation with New York Heart Function Classification
10.3969/j.issn.1004-8812.2017.09.008
- VernacularTitle:肺动脉高压患者压力-容积关系分析与纽约心脏病协会心功能分级的相关性
- Author:
dong Chang ZHANG
1
;
na Shu XIAO
;
ke Xiao SHANG
;
Rong LU
;
jun Li WANG
;
Jun TIAN
;
guo Nian DONG
;
Mei LIU
;
hua Yi LIU
Author Information
1. 武汉亚洲心脏病医院心外科
- Keywords:
Pulmonary hypertension;
Right ventricle;
New York Heart Function Classification;
Pressure volume relationship
- From:
Chinese Journal of Interventional Cardiology
2017;25(9):512-519
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the correlation between the pressure volume parameters and cardiac function in terms of New York Heart Association(NYHA) classification in patients with pulmonary arterial hypertension. Methods Among 36 patients with pulmonary hypertension admitted in our center between April 2015 to June 2016, right heart catheterization recording right atrial pressure curve,right ventricular pressure curve,pulmonary arterial pressure and oxygen saturation curve in different parts was performal.All patients recived underwent cardiac MRI examination to obtain a single cardiac cycle and the use of Mass software to measure right ventricular volume continuously and right ventricular pressure-volume loop parameters were then obtained. Patients were divided into different groups according to the NYHA functional classification, and the correlation between the parameters of each group and the cardiac function classes a were analyzed. Results Compare to patients with NYHA class Ⅰheart function,patients with NYHA heart function class Ⅱ and class Ⅲ had significantly higher right ventricular end diastolic pressure(P < 0.05)and higher right ventricular systolic pressure (P < 0.01). Spearman correlation analysis showed that cardiac function of NYHA classⅠ,Ⅱ and Ⅲhad position correlation with RVESV,RVEDP and RVESP wheras negative correlation with RVEDV. ROC curve analysis showed that,when the patients were divided into 2 groups as NYHAⅠvs. NYHA class Ⅱ + Ⅲ,NYHA classification for predicting the outcome of the NYHA class Ⅱ + Ⅲ level, pulmonary artery elasticity and right ventricular end systolic pressure had larger area under curves respectively. Conclusions Pressure-volume parameters of right ventricles are more objective indicators for cardiac function assessment for pulmonary hypertension patients and evaluation of disease progression especialy in patients with mild symptoms.
