Research progress and prospect of the relationship between homeodox genes' family and development of digestive system tumors
10.3760/cma.j.issn.1673-4203.2017.08.016
- VernacularTitle:同源异形盒基因家族与消化系统肿瘤关系研究进展及前景探讨
- Author:
Zhiwei QIN
1
;
Chenlong SONG
;
Chongzhi ZHOU
Author Information
1. 上海交通大学附属第一人民医院
- Keywords:
Digestive system;
Neoplasms;
Review;
Homeobox genes
- From:
International Journal of Surgery
2017;44(8):557-561
- CountryChina
- Language:Chinese
-
Abstract:
Homeobox gene is an important gene family of developmental regulatory in the body.It is highly conserved in the evolutionary process.It is widely found in nervous,digestive,respiratory,circulatory,blood and genitourinary system,involved in rcgulating the growth and development of individuals,cells' proliferation,differentiation,apoptosis and other processes.The present studies show that the abnormal expressions of homeobox genes are closely related to the occurrence,development and prognosis of human multiple malignancies.In this paper,the research progress and prospect of the relationship between homeobox genes' family and development of digestive system tumors are reviewed.
