Regulatory effect of LncRNA HOTTIP in digestive system neoplasms
10.3760/cma.j.issn.1673-4203.2017.08.019
- VernacularTitle:长链非编码RNA HOTTIP在消化系统肿瘤中的调控作用
- Author:
Xingming JIANG
1
;
Zhidong WANG
;
Wangyang ZHENG
;
Jinglin LI
;
Zhenglong LI
;
Xinheng LI
;
Yunfu CUI
Author Information
1. 哈尔滨医科大学附属第二医院胆胰外科
- Keywords:
Digestive system neoplasms;
Prognosis;
Review;
Long noncoding RNA;
HOXA distal transcript antisense RNA
- From:
International Journal of Surgery
2017;44(8):568-572
- CountryChina
- Language:Chinese
-
Abstract:
As the crucial member of noncoding RNA family,there is increasing evidence that long noncoding RNA has participated in numerous physiological and pathological processes of organisms.HOXA distal transcript antisense RNA is a long noncoding transcript located at the 5'tip of HOXA.According to research reports,the up-regulation of HOTTIP is closely associated with occurrence and progression of multiple digestive system cancers and promotes the carcinogenesis.The regulatory effect of long noncoding RNA HOXA distal transcript antisense in digestive system neoplasms will be summarized in this article.
