Rationality Evaluation of Clinical Application of Clindamycin Hydrochloride Injection in Orthopedic Inpa-tients of a General Hospital
10.6039/j.issn.1001-0408.2017.29.06
- VernacularTitle:某综合医院骨科住院患者盐酸克林霉素注射剂使用合理性评价
- Author:
Ming YAN
1
;
Weiwei TENG
;
Lan CUI
Author Information
1. 昆明医科大学第二附属医院药学部
- Keywords:
Clindamycin hydrochloride injection;
Orthopedics;
Inpatients;
Rational drug use
- From:
China Pharmacy
2017;28(29):4053-4056
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To provide reference for rational use of Clindamycin hydrochloride injection. METHODS:The utilization of Clindamycin hydrochloride injection in orthopedic inpatients of a third grade class A general hospital dur-ing 2013-2015 was analyzed and investigated retrospectively. The rationality evaluation standard was formulated to evaluate the rationality of drug use in those patients. RESULTS:A total of 189 orthopedic inpatients received Clindamycin hydro-chloride injection,and there were 152 cases of irrational drug use among which there were 16 cases of irrational therapeu-tic drug use and 136 cases of irrational prophylactic drug use. Irrational drug use mainly included irrational usage and dos-age(86.18%),irrational drug selection(44.74%)and irrational drug replacement(15.79%). Two patients suffered from ADE,i.e. rash and nausea. After drug withdrawal and symptomatic treatment,the symptoms were improved,but irrational drug use was found in one case. CONCLUSIONS:The utilization of Clindamycin hydrochloride injection is irrational in or-thopedic department. It is necessary to further standardize medication behavior and guarantee the safety and effectiveness of drug use.
