Precise hepatectomy and irregularity hepatectomy in treatment of primary liver cancer:a comparative study
10.3969/j.issn.1006-5725.2017.20.025
- VernacularTitle:原发性肝癌精准肝切除与不规则性肝切除的对比研究
- Author:
Youan LI
1
;
Qifan ZHANG
;
Qing CAI
;
Guoliang CAO
;
Caihong ZHOU
;
Jie ZHOU
Author Information
1. 南方医科大学南方医院肝胆外科
- Keywords:
primary liver cancer;
precise hepatectomy;
irregularity hepatectomy
- From:
The Journal of Practical Medicine
2017;33(20):3429-3433
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the value of precise hepatectomy in treatment of early-stage primary liver cancer after radical resection. Methods Between June 2012 and July 2014,174 patients undergoing radical resection of hepatocellular carcinoma were enrolled in this comparative study at Nan fang Hospital. 118 patients with liver resection under precise hepatectomy were assigned to precise resection group and 56 patients with liver resection under Pringle maneuver were assigned to occlusion group. The two groups were compared in terms of preoprational clinical pathological and laboratory data ,volume of intraoperative bleeding and blood transfusion , postoperative hepatic function recovery,hospitalization days,and postoperative tumor-free survival rate of 1,2 years. Results There was no significant difference between the two groups in the sex,age,liver disease,preo-pration albumin,ALT,AST,alcohol intake and liver cirrhosis(P>0.05). No differences between the two groups were found about the volume of intraoperative bleeding and blood transfusion as well as surgery cost (P > 0.05). The recovery of hepatic function was accelerated and the incidence of complications ,hospitalization days and peri-od of drainage were significantly reduced in the precise resection group compared with the occlusion group (P <0.05). The 1,2-years postoperative tumor-free survival rate was 79.7%(94/118),60.9%(46/118)in the precise group and 50.0%(28/56),46.4%(26/56) in the occlusion group ,with significant difference between them (χ2=4.741,8.722,P<0.05). Conclusions For early-stage liver cancer patients,the precise hepatectomy during radical resection results in quick recovery and fewer complications ,thus it should be the first choice of clinical operation.