Regional homogeneity of brain in irritable bowel syndrome patient:a resting state fMRI study

VernacularTitle:肠易激综合征基于局部一致性的静息态脑功能成像研究
Author: Meng QIN ¹ ; Qing ZHANG ; Jinbai HUANG
Author Information

1. 长江大学附属第一医院放射科
Keywords: resting-state; irritable bowel syndrome; regional homogeneity; functional magnetic reso-nance imaging
From: The Journal of Practical Medicine 2017;33(20):3455-3458
CountryChina
Language:Chinese
Abstract: Objective To investigate regional homogeneity(ReHo)of brain in patients with irritable bowel syndrome(IBS)using resting-state functional MRI(rs-fMRI). Methods 23 patients with IBS and 23 age-,edu-cation-,and sex-matched normal healthy subjects(control group)were collected in our hospital from July 2015 to June 2016. All of them underwent rs-fMRI. The rs-fMRI data were analyzed with the regional homogeneity method. Results As compared with the control group ,the IBS group showed significantly increased ReHo values in the left occipital lobe,and decreased ReHo values in the right insular,the right superior temporal gyrus and bilateral middle frontal gyrus(P < 0.001). Conclusion One or more brains of the IBS patients showed significant differ-ences in the spontaneous neuronal activity compared with healthy controls.