Effects of different depths of anesthesia on postoperativecognitive dysfunction:a meta-analysis
10.3969/j.issn.1006-5725.2017.20.035
- VernacularTitle:Narcotrend监测不同麻醉深度对术后认知功能障碍影响的Meta分析
- Author:
Shaoling LIANG
1
;
Yawen WU
;
Ruiwen DING
;
Xiuhua TAN
;
Xiaofeng WEI
;
Bulong LI
Author Information
1. 510150,广州医科大学附属第三医院麻醉科
- Keywords:
depth of anesthesia;
narcotrend monitor;
postoperative cognitive dysfunction;
Meta-analysis
- From:
The Journal of Practical Medicine
2017;33(20):3467-3471
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of different depths of anesthesia on incidence of postopera-tive cognitive dysfunction (POCD). Methods We systematically retrievedPubmed,OVID,CNKI,CBM and Wanfang database and VIP database for randomized controlled trials(RCTs)from inceptionto December 312016, comparing different depths of anesthesia for their impacts on incidence of early POCD. After data extraction and quality evaluation,Revman 5.3 software was used for statistical data analysis. Results A total of 714 patients in 8 eligible RCTs were identified. Results of meta-analysis were as follows.(1)Incidence of POCD of depth anesthesia (NTS=E0-E1)was lower than general anesthesia(NTS=D0-D1)1 d after surgery(OR=0.21,95%CI 0.13~0.35,P < 0.00001).(2)Incidence of POCD of depth anesthesia(NTS = E1)was lower than general anesthesia (NTS=D0)7 d after surgery(OR=0.45,95%CI 0.23~0.91,P=0.03).(3)Incidence of POCD of NTS=E1 was lower than NTS=D07d after surgery(OR=0.42,95%CI 0.24~0.71,P=0.001). Conclusion Comparedwith general anesthesia,depth anesthesia is associated with a lower incidence of early POCD.
