A cohort study on treatment of chronic kidney disease 3 with qi deficiency and dampness-heat typebyqing-budigui decoction
10.3969/j.issn.1006-5725.2017.20.036
- VernacularTitle:清补地龟汤治疗气虚湿热型慢性肾脏病3期的队列研究
- Author:
Yuan MENG
1
;
Yuefen WANG
;
Dong CHEN
;
Yu WANG
;
Wenjing ZHAO
;
Binghou ZHANG
;
Cuiyan LYU
Author Information
1. 首都医科大学附属北京中医医院肾病科
- Keywords:
chronic kidney disease 3;
qingbudigui decoction;
qi deficiency and dampness heat;
type of syndrome;
cohort study
- From:
The Journal of Practical Medicine
2017;33(20):3472-3476
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical effects of the treatment on chronic kidney disease 3 with dampness-heat type. Methods A retrospective cohort study recruited 103 patients with qi deficiency and dampness-heat type of CKD3. Among them,51 cases in the control group were treated with western medicine therapy. The 52 cases in the treatment group received Qingbudigui Decoction. SCr ,eGFR and 24hU-Prowere were observed after 12 months and 24 months for evaluating the clinical effects of Qingbudigui Decoction. Results After 12 and 24 months treatment,the treatment group had a significantly lower SCr and U-Pro(P < 0.01),but a higher eGFR (P<0.01,P<0.05). After 12 months and 24 months,there was no significant change in SCr,U-Pro or eGFR in the control group (P > 0.05). Conclusions Combination therapy of the Qingbudigui Decoction of the patients with qi deficiency and dampness-heat type of CKD3 could delay the kidney disease,which is superior to simple western medicine group. The mechanism may be related to the reduction of urinary protein excretion.
