Advances in the immunotherapy of glioma
10.3969/j.issn.1000-8179.2017.18.281
- VernacularTitle:胶质瘤免疫治疗新进展
- Author:
YI LI
1
;
TAO ZHENNAN
;
YANG XUEJUN
Author Information
1. 天津医科大学总医院神经外科 天津市300052
- Keywords:
glioma;
immunotherapy;
checkpoint;
tumor vaccine
- From:
Chinese Journal of Clinical Oncology
2017;44(18):931-934
- CountryChina
- Language:Chinese
-
Abstract:
Tumor immunotherapy refers to the application of immunological principles and methods to stimulate and enhance the body's antitumor immune response as well as assist the immune system to kill tumors and inhibit tumor growth.These methods in-volve injecting immune cells and effector molecules into the host.Immunotherapy,especially immunoprecipitation treatment,has ex-erted a strong antitumor effect on melanoma,renal cell carcinoma,non-small cell lung cancer,and hematological malignancies.This method has also received widespread attention.However,in malignant glioma,immunotherapy is still in its infancy.Numerous clinical trials have shown that immunotherapy for glioma is feasible and safe.This paper reviews the latest advances in immunization strate-gies,such as immunological checkpoints,adoptive immunotherapy,and tumor vaccines,to provide new ideas for glioma treatment.
