Application and correlation of HCY ,CF-6 and UMA levels in diagnosis and treatment of coronary heart disease complicated with heart failure
10.3969/j.issn.1673-4130.2017.18.010
- VernacularTitle:3种指标在冠心病合并心力衰竭诊治中的应用及相关性研究
- Author:
Zhaodi YANG
1
;
Suqing WANG
;
Guangyan XI
Author Information
1. 河北省唐山市工人医院分院
- Keywords:
HCY;
CF-6;
UMA;
coronary heart disease;
heart failure;
application effect;
correlation
- From:
International Journal of Laboratory Medicine
2017;38(18):2526-2528
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect and correlation of serum homocysteine(HCY),mitochondrial coupling factor-6 (CF-6) and urine trace protein(UMA) level in the diagnosis and treatment of coronary heart disease complicated with heart failure.Methods From June 2012 to June 2016 in Tangshan City worker's Hospital of Hebei Province branch from coronary heart disease with heart failure in 200 cases,as the observation group,patients received conventional treatment,according to the results of treatment were divided into effective group(n=168) and ineffective group (n=32).The treatment of hospitalized patients with coronary heart disease and heart failure in 100,set to the coronary heart disease group and heart failure group.At the same time,100 cases were admitted in the same period of healthy people as the healthy control group.Serum HCY levels were determined by enzymatic cycling method.Analysis of serum CF-6 level was detected by radioimmunoassay,using immune scattering to detect urine UMA turbidity,HCY,CF-6,UMA analysis and observation of the level of diagnosis and treatment of coronary heart disease in patients with heart failure.Results HCY,CF-6 and UMA in the observation group,CHD group,heart failure group were significantly higher than that of the control group,and the difference was statistically significant(P＜0.05),There was no significant difference in coronary heart disease group and heart failure group in HCY,CF-6 and UMA level(P＞0.05).HCY,CF-6 and UMA in the observation group were significantly higher than that of patients with coronary artery disease and heart failure group,and the difference was statistically significant(P＜0.05).HCY,CF-6 and UMA levels of effective group and ineffective group were higher than the control group,and the difference was statistically significant(P＜0.05).HCY,CF-6,UMA effective level in invalid group were low,and the difference was statistically significant(P＜0.05).There was a positive correlation between rate of coronary heart disease with heart failure and HCY,CF-6 and UMA(P＜0.05).Conclusion The detection of serum HCY,CF-6 and UMA levels in patients with coronary heart disease complicated with heart failure may play a role in the observation of the curative effect.
