Reference intervals for plasma presepsin in healthy elderly adults
10.3969/j.issn.1673-4130.2017.18.011
- VernacularTitle:健康成年人血浆presepsin正常值参考区间调查
- Author:
Zhaotao ZHANG
1
;
Xiaoping LIU
;
Meng HUANG
;
Xingwei LUAN
;
Jiajin YANG
Author Information
1. 莱西市中医医院检验科
- Keywords:
soluble CD14 subtype;
healthy adult;
reference intervals
- From:
International Journal of Laboratory Medicine
2017;38(18):2529-2531
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish the reference intervals(RIs) for plasma presepsin in healthy population.Methods The document C28-A3 issued by CLSI was a guideline about how to define,establish,and verify reference intervals in the clinical laboratory.Plasma values were determined with CLEIA for 1 250 healthy adults(aged 20-90 years old),including 624 males and 626 females.The central 95 percentile of RIs were determined using nonparametric statistical methods.Results The presepsin values in elderly population showed a Gaussian distribution and age/sex related changes.The RIs for plasma presepsin in the reference population respective of age(ranged from 20-＜30,30-＜ 60,60-＜ 90 years) were 50-195,47-170,41-142 pg/mL for males and 43-173,44-162,38-137 pg/mL for females respectively.Conclusion The RIs for plasma presepsin were established according to the gender and age groups in the healthy adults,and could provide a reference for the clinical and laboratory.
