The research about changes of thyroid function in patients with depression
10.3969/j.issn.1673-4130.2017.18.021
- VernacularTitle:抑郁症患者甲状腺功能变化的研究
- Author:
Guangquan LI
1
;
Weidong ZHOU
;
Yong HE
;
Xin NIE
;
Guixing LI
Author Information
1. 三六三医院检验科
- Keywords:
depression;
thyroid function;
thyroid-stimulating hormone;
free triiodothyronine;
free thyroxine
- From:
International Journal of Laboratory Medicine
2017;38(18):2556-2558
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study thyroid function in patients with depression.Methods The average levels of TSH,FT3,FT4 in 5 316 patients with depression were compared with 5 316 healthy controls.The average levels of TSH,FT3,FT4 were compared between male and female patients with depression.The differences of thyroid disease detection rate were compared between elder and group younger group.Results The differences of TSH,FT3,FT4 levels between the depression patients and healthy controls have statistically significant(P<0.05).The differences of TSH,FT3,FT4 levels between the male depression patients and the female depression patients have statistically significant (P< 0.05).The hyperthyroidism prevalence were as follows:6.50 % versus 6.10 % (P>0.05),compared between older and younger depression patients.The subclinical hypothyroidism prevalence 24.30 % versus 9.40 % (P<0.05),compared between older and younger depression patients.The hypothyroidism prevalence 14.30 % versus 2.90% (P<0.05),compared between older and younger depression patients.Conclusion Depression is easily caused by low thyroid hormone levels.Women and elder people with hypothyroidism should more prevent depression.Thyroid hormones can be used as routine screening index of depression,but not specific indicators.