Pathogens distribution and resistance of clinical specimens in neonatal department
10.3969/j.issn.1006-5725.2017.17.016
- VernacularTitle:住院新生儿临床分离病原菌及其耐药性分析
- Author:
Jingjing LI
1
;
Miaoling LIU
;
Fei WU
;
Jianying HUANG
;
Xiaoni ZOU
Author Information
1. 广东省妇幼保健院医院感染管理科
- Keywords:
pathogens;
drug susceptibility testing;
antibiotic resistance;
neonates
- From:
The Journal of Practical Medicine
2017;33(17):2869-2872
- CountryChina
- Language:Chinese
-
Abstract:
Objectives To analyze the distribution and drug resistance of pathogenic bacteria in neonatal department,and to provide criteria for rational clinical use of antibiotics. Methods Totally 15,796 specimens ob-tained from neonates were cultured according to the operation specification. The isolated pure strains were identified and their drug susceptibility was tested by VITEK-2 automated microorganism identification system. Results A to-tal of 1,125 strains of bacteria were isolated and the total detection rate was 7.1%. Of the total,742(66.0%)were gram-negative bacteria ,355(31.6%)gram-positive bacteria and 28(2.4%)fungi. K pneumonia was the most fre-quently isolated pathogen in gram-negative bacteria ,and staphylococcus the most frequently isolated pathogen in gram-positive bacteria. G-bacteria were highly resistant to ampicillin ,1st and 2nd generation cephalosporin. The re-sistant rates of K pneumonia,P aeruginosa and A baumannii to imipenem were>24.0%.Among the staphylococ-cus,35.7%were MRSA and 73.3%MRSCN. The antibiotic sensitivities of staphylococcusto vancomycin,Rina thia-zole alkanes and Tigecycline were 100.0%,but those to penicillin,cephalosporin and erythromycin low. Conclu-sion The dominant bacteria isolated from specimens obtained from neonates are gram-negativebacteria ,and they present extensive antibiotic resistance.
