Comparative evaluation of liver MRE and DWI on staging hepatic fibrosis in patients with chronic hepati-tis B
10.3969/j.issn.1006-5725.2017.17.032
- VernacularTitle:磁共振弹力成像与扩散加权成像诊断慢性乙型病毒性肝炎纤维化程度分级的对比
- Author:
Lingrong PENG
1
;
Zhanao MENG
;
Jin WANG
;
Jianing CHEN
;
Weimin LIU
Author Information
1. 中山大学附属第三医院放射科
- Keywords:
magnetic resonance elastography;
diffusion-weighted imaging;
Hepatitis B
- From:
The Journal of Practical Medicine
2017;33(17):2930-2933
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the diagnostic value of MRE and DWI in staging hepatic fibrosis in pa-tients with CHB. Methods In this retrospective analysis ,we investigated 93 patients with CBH and live fibrosis. Ninety-three patients were grouped according to their pathological grading of fibrosis ,from S0 to S4. Sixteen healthy patients were enrolled as the control group. Spearman correlation analysis was used to analyze the correla-tion between the stiffness and ADC value and their staging fibrosis. ROC analysis was conducted to compare the per-formance of the stiffness and ADC value in staging hepatic fibrosis. Results Both liver stiffness value(r=0.962, P<0.01)and ADC value(r=-0.823,P<0.01)were highly correlated with the stage of liver fibrosis. The area un-der ROC(AUC)for the detection of≥S1≥S2/≥S3/S4 stage fibrosis with the stiffness and ADC value were 0.963/0.868、0.995/0.947、0.998/0.948、0.996/0.889 respectively ,with statistically significant differences (P < 0.05 , resectively). Conclusions MRE and DWI have higher value ,and MRE is more accurate than DWI for staging hepatic fibrosis in patients with CHB.
