Effect of dexmedetomidine on the stress reaction for awake nasotracheal intubation in patients with maxil-lofacial tumor
10.3969/j.issn.1006-5725.2017.17.028
- VernacularTitle:右美托咪啶对口腔颌面肿瘤根治术患者经鼻清醒插管应激反应的影响
- Author:
Xuefang DU
1
;
Yang ZHAO
;
Lei CHEN
;
Yuewei FAN
;
Qiongmei GUO
Author Information
1. 河北省眼科医院麻醉科
- Keywords:
dexmedetomidine;
conscious sedation;
intubation;
intratracheal;
mouth neoplasms
- From:
The Journal of Practical Medicine
2017;33(17):2915-2917
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the Effect of dexmedetomidine on the stress reaction for awake nasotra-cheal intubation in patients with maxillofacial tumor. Methods Forty patients,which are ASA physical status Ⅰor Ⅱ,aged 20 ~ 62 yr ,BMI < 25 and scheduled for radical operation for maxillofacial tuomr ,were randomly divided into 2 groups (n = 20 each)using a random number table:dexmedetomidine groups(group D)and mid-azolam group(group M). MAP ,HR ,SpO2 were recorded ,and the rate of respiratory depression ,the degree of tolerance and matching and the memory to intubation were recorded. Results Compared with the baseline value at T0,MAP and HR at T1-2 and HR at T3 were increased in group M. HR were increased at T1 in group D(P<0.05). Compared with group M,MAP and HR at T1-2 and HR at T3 were decresed in group D(P<0.05). The rate of respi-ratory depression in group D was decreased compared with group M ,and the degree of tolerance and matching to intubation was better in group D. Conclusion dexmedetomidine can inhibit the stress reaction caused by nasotra-cheal intubation in patients with maxillofacial tuomr ,and improve the degree of comfort and security in the process of intubation.
