Effects of Acupuncture Treatment on HPA Axis Related Hormones in Insomnia Rats
10.3969/j.issn.1005-5304.2017.11.013
- VernacularTitle:按经选穴针刺对失眠大鼠下丘脑-垂体-肾上腺皮质轴相关激素的影响
- Author:
fen Xue WU
1
;
hui Zeng YUE
;
na Xue ZHENG
;
Xin GUO
;
qiang Zhi XIE
;
na Li XIE
Author Information
1. 湖南中医药大学
- Keywords:
acupuncture;
insomnia;
HPA axis;
acupoints at different meridians;
acupoints compatibility;
rats
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2017;24(11):53-57
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effects of acupuncture treatment on the levels of HPA axis related hormones and acupoint compatibility in insomnia rats; To discuss the mechanism of action for acupuncture treatment. Methods Chlorophenylalanine suspension was under intraperitoneal injection to establish insomnia model rats. Sixty SD rats were randomly divided into blank group, model group, Baihui+Shenmen group, Baihui+Sanyinjiao group, Baihui+non-acupoint group, with 12 rats in each group. Each treatment group received acupuncture in relevant acupoints, 30 min each time, for 7 d. ELISA was used to measure the levels of CRH, ACTH and CORT. Results Compared with the model group, the levels of CRH, ACTH and CORT of the acupuncture groups decreased to some extent. In the three acupuncture groups, the efficacy of Baihui+Shenmen group was better than that of Baihui+Sanyinjiao group and Baihui+non-non-acupoint group. Conclusion Acupuncture treatment may calm and soothe the nerves to release the insomnia through regulating HPA axis related hormones. Acupuncture acupoints at different meridians may be one of the factors that cause the difference of acupoints compatibility effect.
