Analysis of clinical characteristics of different degrees of myocardial noncompaction in children
10.3969/j.issn.1000-3606.2017.10.009
- VernacularTitle:儿童不同程度心肌致密化不全临床特点分析
- Author:
Huiming ZHOU
1
;
Lingjuan LIU
;
Yao WU
;
Tiewei LYU
;
Jie TIAN
Author Information
1. 重庆医科大学附属儿童医院心内科 儿童发育疾病研究教育部重点实验室 儿童发育重大疾病国家国际科技合作基地 儿科学重庆市重点实验室 重庆 400014
- Keywords:
noncompaction of ventricular myocardium;
clinical characteristics;
outcome;
child
- From:
Journal of Clinical Pediatrics
2017;35(10):751-754
- CountryChina
- Language:Chinese
-
Abstract:
Objectives To explore the clinical characteristics and prognosis of different degrees of noncompaction of ventricular myocardium (NVM) in children and to investigate the clinical significance of the ratio of the thickness of the non-compact myocardium to the dense myocardium (N/C). Methods The clinical data of the children with NVM were analyzed retrospectively. The differences between children with N/C > 2.0 and children with N/C 1.4~2.0 were compared. Results There were 26 children in each of the two groups. There was no significant difference in age, sex, the ratios of low birth weight and malnutrition, heart disease, and complication (P all > 0.05). When discharged, 8 cases were improved, 15 cases has no obvious improvement, and 3 cases died in N/C>2.0 group; while 18 cases were improved, 8 cases has no obvious improvement, and none died in N/C 1.4~2.0 group, and the effective rate of treatment between two groups was statistically difference (χ2=7.69,P=0.006). In 8 years of follow-up, the mortality rate in N/C > 2.0 group was higher than that in N/C 1.4~2.0 group, and the difference was statistically different (χ2=6.993, P=0.008). Conclusions The treatment efficiency was lower and the prognosis was worse when the N/C value was higher in children with NVM.
