Postoperative analgesia of Ropivacaine combined Dexmedetomidine for transversus abdominis plane block in laparoscopic surgery
10.3969/j.issn.1007-1989.2017.10.004
- VernacularTitle:罗哌卡因加右美托咪定腹横肌平面阻滞用于腹腔镜术后镇痛的效果研究
- Author:
Zhang LI
1
;
Yuan JUN
;
Li JI-YONG
;
Chen XI
;
Deng FANG-FANG
;
Yu LE
Author Information
1. 湖北省武汉市第一医院 麻醉科
- Keywords:
Dexmedetomidine;
transversus abdominis plane block;
analgesia;
laparoscopic hernia repair
- From:
China Journal of Endoscopy
2017;23(10):16-20
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of postoperative analgesia of Ropivacaine combined Dexmedetomidine for transversus abdominis plane (TAP) block in laparoscopic surgery. Methods 60 patients underwent selective laparoscopic hernia repair were randomly divided into two groups: Ropivacine plus Dexmedetomidine group (Rpd group): Dexmedetomidine 1.0 μg/kg + 0.4% Ropivacine 30 ml was injected into bilateral TAP, and Ropivacine group (R group): saline 1 ml+0.4% Ropivacine 30 ml was injected into bilateral TAP. Blood pressure and heart rate on beginning of the surgery, 1 h during surgery and leaving the operating room, VAS of immediate postoperative period, 4 h, 6 h, 8 h, 12 h, 24 h after the surgery, analgesic duration and incidence of nausea and vomiting of the two groups were recorded. Results Two groups have no difference in blood pressure and heart rate in all time points (P > 0.05), VAS score of 6 h, 8 h, 12 h after surgery in Rpd group were lower than in R group (P < 0.05), and VAS score of postoperative period, 4 h, 24 h after the surgery had no difference between the two groups (P > 0.05). Sensory block duration in Rpd group was longer than in R group (P < 0.05). Incidence of nausea and vomiting of the two groups had no difference in two groups (P > 0.05). Conclusions Ropivacaine combined Dexmedetomidine for Transversus Abdominis Plane block in laparoscopy patients can significantly prolong the analgesic duration.