Clinicopathological analysis of endoscopic submucosal dissection for esophageal mucosa lesion
10.3969/j.issn.1007-1989.2017.10.007
- VernacularTitle:食管黏膜病变内镜黏膜下剥离术前和术后的临床病理分析
- Author:
Zhuang JIE
1
;
Wu HONG-LEI
;
Wang HONG-BO
;
Wang HONG-JUAN
;
Chen ZHAO-SHENG
;
Guo JIAN-QIANG
;
Xu WEI-HUA
Author Information
1. 山东大学第二医院 消化内科
- Keywords:
early esophageal carcinoma;
intraepithelial neoplasia;
endoscopic submucosal dissection (ESD)
- From:
China Journal of Endoscopy
2017;23(10):31-36
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the endoscopic and clinicopathologic features of early esopheal carcinoma and precancerous lesions and evaluate the necessity, efficacy and safety of ESD in the treatment. Methods From May 2013 to April 2016, 51 consecutive patients underwent high-resolution video endoscopy and biopsy, confirmed diagnosis of early esophageal squamous cell carcinoma or intraepithelial neoplasia were included. There were capillary loops (IPCL), iodine-staining, preoperative and postoperative pathology, and complications to analyze. Results 51 patients had total 58 lesions, Type A, Type B1, Type B2 of IPCL classification were diagnosed in 8 (13.79%), 44 (75.86%), 6 (10.34%). Low-grade intraepithelial neoplasia (LGIN), high-grade intraepithelial neoplasia, early esophageal carcinoma of preoperative biopsy were diagnosed in 11 (18.97%), 42 (72.41%), 5 (8.62%), low-grade intraepithelial neoplasia (LGIN), high-grade intraepithelial neoplasia, early esophageal carcinoma of postoperative pathology results were diagnosed in 10 (17.54%), 27 (46.55%), 21 (36.21%), concordance rate of pathological results were 60.34%. Complications included micro-perforations (0.00%), strictures (8.62%) and delayed hemorrhage (3.51%), respectively. Conclusion After endoscopic submucosal dissection, detection rate of early esophageal cancer increased significantly, preoperative biopsy had guidance significance in diagnosis and treatment, ESD treatment can reduce the missed diagnosis of early esophageal carcinoma.
