Simultaneous Determination of Benzaldehyde and Menthol in Jingdu Niancian Milian Chuanbei Pipagao by Quantitative Analysis of Multi-components by Single Marker
- VernacularTitle:一测多评法测定京都念慈菴蜜炼川贝枇杷膏中苯甲醛和薄荷脑含量
- Author:
Junzhong HUANG
1
;
Lanhua ZENG
;
Gaopian CHEN
;
Li QIU
Author Information
1. 广东省药品检验所 广州510180
- Keywords:
Quantitative analysis of multi-components by single marker;
Jingdu Niancian Milian Chuanbei Pipagao;
Related cor-rection factor;
Benzaldehyde;
Menthol;
GC
- From:
China Pharmacist
2017;20(10):1881-1883
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To establish a quality control method for Jingdu Niancian Milian Chuanbei Pipagao by quantitative analysis of multi-components by single marker ( QAMS) . Methods:GC was used with benzaldehyde as the internal standard,and the relative calibration factor of benzaldehyde and menthol was establish by GC and used for the content calculation of menthol by QAMS. Mean-while,the results of QAMS and those of the external standard method were compared. The effects of different instruments and chromato-graphic columns were studied to evaluate the accuracy and scientificity of QAMS applied in compound preparations. Results:No signif-icant differences in the quantitative results of benzaldehyde and menthol were found between the external standard method and QAMS. Conclusion:It is feasible and suitable to evaluate the quality of benzaldehyde and menthol in Jingdu Niancian Milian Chuanbei Pipagao by QAMS.
