Research progress in metabolic bone disease of prematurity
10.3969/j.issn.1000-3606.2017.10.017
- VernacularTitle:早产儿代谢性骨病研究进展
- Author:
Xiaona LUO
1
Author Information
1. 上海交通大学医学院附属上海儿童医学中心 上海 200127
- Keywords:
preterm;
metabolic osteopathy;
calcium and phosphorus metabolism
- From:
Journal of Clinical Pediatrics
2017;35(10):788-792
- CountryChina
- Language:Chinese
-
Abstract:
Metabolic bone disease of prematurity (MBDP) is an important chronic disease in the neonates. The metabolic abnormalities of calcium, phosphorus, vitamin D and others in premature can lead to decline of bone mineral content, decrease of trabecular bone quantity, thinning of cortical bone, etc., which can cause rickets in severe cases and even fracture. Low gestational age and low birth weight of premature are important risk factors for metabolic bone disease. The diagnosis relies on clinical features as well as laboratory, radiological and ultrasonographic examinations. The treatment includes reinforcement of the passive movement, supplementiation of the calcium, phosphorus and vitamin D, better prevention and so on. Early detection, early diagnosis, and early treatment can reduce the incidence of sequelae of metabolic bone disease, and reduce the long-term impact on premature infants.
