Clinical analysis of non-ketotic hyperglycemia chorea
10.3969/j.issn.1002-0152.2017.08.010
- VernacularTitle:非酮症性高血糖合并舞蹈症6例临床分析
- Author:
Jianfeng QU
1
;
Yazhi WANG
;
Yonglin LIU
;
Yangkun CHEN
;
Weimin XIAO
Author Information
1. 东莞市人民医院神经内科 东莞523000
- Keywords:
Chorea;
Non-ketotic hyperglycemia;
Diabetes mellitus;
Magnetic resonance imaging
- From:
Chinese Journal of Nervous and Mental Diseases
2017;43(8):496-499
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical manifestation,neuroimaging characteristics and follow-up results of chorea associated with non-ketotic hyperglycemia (C-H-BG).Methods Clinical data of six patients with C-H-BG were analyzed retrospectively.Results The average age of the six patients (five female and one male) was 65.8±13.9 years,All patients had acute-subacute course.Patients presented with choreic movements involving facial muscles (n=6) and unilateral (n=5) or bilateral limbs (n=1).The average value of plasma glucose at admission was 9.21 ± 5.15 mmol/L.All patients had significantly elevated HbA1c (14.1 ±3.5％).The brain MRI T1 imaging from all patients showed hyperintensity in the basal ganglia,putamen,lenticular nucleus and caudate nucleus.SWI imaging revealed corresponding hypointensity signal in the basal ganglia in three patients.Two patients had severe stenosis of the MCA.Five patients were followed up for an average of 16.2 ±7.2 months.Three patients died.Conclusion The high T1 hypertense lesions in the basal ganglia are the mainly radiological feature of C-H-BG which may be accompanied by SWI hytointense signals in the basal ganglia.
