A Case of Aplasia Cutis Congenita after Methimazole Exposure during Pregnancy.
- Author:
Gun PARK
1
;
Hee Jung KIM
;
Hyo Chan JANG
;
Hyun CHUNG
Author Information
1. Department of Dermatology, School of Medicine, The Catholic University of Daegu, Daegu, Korea. g9563009@cu.ac.kr
- Publication Type:Case Report
- Keywords:
Aplasia cutis congenita;
Methimazole
- MeSH:
Cicatrix;
Congenital Abnormalities;
Ectodermal Dysplasia*;
Female;
Fertile Period;
Humans;
Infant;
Methimazole*;
Mothers;
Parturition;
Pregnancy*;
Propylthiouracil;
Scalp;
Skin
- From:Korean Journal of Dermatology
2006;44(5):642-644
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Aplasia cutis congenita is a rare congenital defect in which localized or widespread areas of the skin are singly or multiply absent or already scarred at birth. Multiple etiologies have been suggested for the cause, however, methimazole exposure during pregnancy has rarely been postulated as the cause of aplasia cutis congenita. We report a case of an infant with scalp aplasia cutis congenita, whose thyrotoxic mother was treated with methimazole during the first 9 weeks of gestation. The casual relationship between the drug and the skin defect is still a matter of debate, therefore, propylthiouracil treatment appears to be preferable to methimazole during the fertile period.
