The study of intertemporal decision-making of schizophrenia and their unaffected siblings
10.3969/j.issn.1002-0152.2017.08.005
- VernacularTitle:精神分裂症患者及其未发病一级亲属跨期决策的研究
- Author:
Lu WANG
1
;
Kongliang HE
;
Xiaomeng BAI
;
Tongjian BAI
;
Huijuan MA
;
Guixian XIAO
;
Xingui CHEN
;
Kai WANG
Author Information
1. 安徽医科大学第一附属医院神经内科 合肥230032
- Keywords:
Schizophrenia;
Intertemporal choice;
Delay-discount;
Siblings
- From:
Chinese Journal of Nervous and Mental Diseases
2017;43(8):470-474
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore whether the ability of intertemporal choice is impaired in schizophrenic patients and in their unaffected siblings.Methods Twenty-five schizophrenia patients,twenty-five unaffected siblings of patients and thirty healthy controls were recruited in the study."Delay-discounting" task and a battery of cognitive neuropsychological assessment were used to examine the intertemporal decision-making.Results (1) the value of k was ((0.005±0.009 in schizophrenia,0.011±0.014 in unaffected siblings and 0.024±0.029 in healthy controls,respectively.There was significant difference in k value among these three groups (F=9.487,P＜0.001).There were significant differences in k value between patients group and healthy controls,and between unaffected siblings and healthy controls (P＜0.05).There was no significant difference between schizophrenia and their unaffected siblings (P＜0.05).(2) Pearson correlation analysis not showed any relationship between neuropsychological test and the value of k.Conclusion The ability of intertemporal choices is impaired in schizophrenia and their unaffected siblings to a great degree.
