Dosimetric analysis of three kinds of irradiation technique in radiotherapy of medulloblastoma
10.11904/j.issn.1002-3070.2017.05.009
- VernacularTitle:三种照射技术在髓母细胞瘤放射治疗中的剂量学分析
- Author:
Helong WANG
1
;
Weikang YUN
;
Yewei WANG
;
Lina FENG
;
Yanling BAI
Author Information
1. 哈尔滨医科大学附属肿瘤医院放射物理科
- Keywords:
Intensity modulated radiation therapy;
Volumetric modulated arc therapy;
Helical tomotherapy
- From:
Practical Oncology Journal
2017;31(5):436-440
- CountryChina
- Language:Chinese
-
Abstract:
Objective We aimed to explore the difference of dosimetry among intensity modulated radia-tion therapy(IMRT),volumetric modulated arc therapy(VMAT)and helical tomotherapy(TOMO)in the radio-therapy of medulloblastoma.Methods Ten children's patients with the medulloblastoma were selected and de-signed in this study.A clinically feasible radiotherapy plan was designed for IMRT(5 fields),VMAT and TOMO. Conformality index(CI),homogeneity index(HI),V107,maximum dose(Dmax),organ at risk(OAR)dose-volume level,monitor units and treatment time were used to analyze in these groups.Results CI,HI,V107,Dmaxand OAR of target areas were significantly superior to VMAT and IMRT in the TOMO group of target PTV for whole brain full radiotherapy.The organ at risk dose-volume level in the TOMO group was lower than that in VMAT and IM-RT(5 fields)groups(P<0.05).The TOMO group also had the most monitor units and the longest treatment time (P<0.05).Hence,the patients in the TOMO group could irradiate completely the whole brain and full spinal cord without moving treatment couch to avoid the error from the man-made movement in VMAT and IMRT(5 fields)treatments.Conclusion In the radiotherapy of medulloblastoma,the dose distribution of patients in the TOMO group are superior to the VMAT and IMRT groups(5 fields).However,the number of monitor units and treatment time is significantly increased during treatment,and its clinical effect needed to be further studies.
