Influence of telmisartan combined amiodarone on blood pressure,left atrial and AF recurrence in pa-tients with hypertension complicated AF
10.3969/j.issn.1008-0074.2017.05.18
- VernacularTitle:替米沙坦并胺碘酮对高血压伴房颤患者血压、 左心房及房颤的影响
- Author:
jian Zhi HE
1
Author Information
1. 广州市南沙区第一人民医院内科
- Keywords:
Hypertension;
Atrial fibrillation;
Amiodarone;
Telmisartan
- From:
Chinese Journal of cardiovascular Rehabilitation Medicine
2017;26(5):526-529
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore influence of telmisartan combined amiodarone on blood pressure,left atrial diame-ter and recurrence of atrial fibrillation (AF)in patients with hypertension complicated AF.Methods:A total of 186 patients with hypertension complicated AF treated in our hospital from Jan 2014 to Jan 2016 were selected.They were randomly and equally divided into amlodipine group (received amlodipine combined amiodarone)and telmisar-tan group (received telmisartan combined amiodarone),the course of treatment was six weeks for both groups. Changes of blood pressure and left atrial diameter before and after treatment,and AF recurrence within six months were observed and compared between two groups.Results:Compared with before treatment,there were significant reductions in systolic blood pressure,diastolic blood pressure and left atrial diameter in both groups after treatment, P <0.01 all;compared with amlodipine group after treatment,there were significant reductions in blood pressure [(137±6)/ (85±7)mmHg vs.(122±5)/ (77±8)mmHg],left atrial diameter [(38.7±2.3)mm vs.(35.3 ±3.4)mm]and AF recurrence rate within six months (37.6% vs.22.6%)in telmisartan group,P <0.01 all. Conclusion:Compared with amlodipine combined amiodarone group,telmisartan combined amiodarone can more significantly reduce blood pressure and left atrial diameter,and significantly reduce recurrence rate of atrial fibrilla-tion in patients with hypertension complicated atrial fibrillation,which is worth extending.
