A Case of Prader-Willi Syndrome with Diabetes Mellitus.
- Author:
Hee Ran CHOI
;
Eun Ha CHOI
;
Seong Hee JANG
;
Young Min AHN
- Publication Type:Case Report
- MeSH:
Adolescent;
Chromosomes, Human, Pair 15;
Diabetes Mellitus*;
Female;
Humans;
Hypogonadism;
Incidence;
Intellectual Disability;
Muscle Hypotonia;
Obesity;
Prader-Willi Syndrome*
- From:Journal of the Korean Pediatric Society
1994;37(4):565-572
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Prader-Willi syndrome is characterized by infantile hypotonia, mental retardation, hyperhagia, hypogonadism and obesity. Approximately 60% of all PLW syndrome show an interstitial deletion of chromosome 15, 37% have apparently normal chromosome, and 3.6% have a variety of other abnormalities involving chromosome 15. Diabetes mellitus has been considered a component of PLW syndrome and the incidence is about 7%. We experienced a 17-year-old female who revealed mental retardation, hypogonadism, obesity, and non-insulin dependent type DM, compatible with Prader-Willi syndrome.
