A Case of Chronic Renal Failure in a Polydipsic Schizophrenic Patient caused by Chronic Anticholinergic Therapy.
- Author:
Il Young CHON
1
;
Dong Joon OH
;
Seung Jin CHOI
;
Ji Young KIM
;
Keryun AHN
;
Won Joon LEE
;
Ji Yeon LEE
;
Haeri BAEK
;
Eunji LEE
;
Sangwon HAN
;
Chan Bok LEE
;
Sang Eun PARK
;
Byoungkook IM
Author Information
1. Department of Internal Medicine, Sam Anyang Hospital, Anyang, Gyeonggi-do, Korea. thekidney@korea.com
- Publication Type:Case Report
- Keywords:
Anticholinergics;
Chronic renal failure;
Urinary retention
- MeSH:
Antipsychotic Agents;
Cholinergic Antagonists;
Contracts;
Dilatation;
Humans;
Hydronephrosis;
Kidney Failure, Chronic;
Muscles;
Neck;
Polydipsia;
Receptors, Muscarinic;
Schizophrenia;
Urinary Bladder;
Urinary Retention
- From:Korean Journal of Nephrology
2009;28(6):658-662
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Anticholinergic drugs block muscarinic receptors at the detrusor muscle of the bladder. It can cause urinary retention by contracting the bladder neck. Cases of hydronephrosis, bladder dilatation as a result of polydipsia while taking anticholinergic drugs have been reported, but very few cases of chronic renal failure can be found. We report a case of a polydipsic schizophrenic patient who, after taking anticholinergic drugs as antipsychotic drugs to treat his schizophrenia for a long time, presented with chronic renal failure due to functional obstructive uropathy in the absence of demonstrable anatomic causes of obstruction.
