Recent updates on extranodal NK/T-cell lymphoma.
- Author:
Won Seog KIM
1
Author Information
1. Department of Internal Medicine, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Korea
- Publication Type:Review ; Clinical Trial
- Keywords:
Extranodal NK/T-cell lymphoma
- MeSH:
Lymphoma;
P-Glycoprotein
- From:Korean Journal of Medicine
2009;77(5):565-570
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Extranodal NK/T-cell lymphoma (ENKL) is a rare subtype of NHL (Non-Hodgkin lymphoma]. It occurs mostly in the nasal and paranal areas. Most of the cases are presented stage I/II. International prognostic index (IPI) can predict the outcome. However, better prognostic model is available such as NKIPI. Because of high expression of p-glycoprotein, ENKL is refractory to chemotherapy. Early stage disease can be bestly treated with concurrent chemoradiation. For advanced stage disease, new clinical trials are now being conducted.
