Development of metabonomics of drug dependence
10.3760/cma.j.issn.1674-6554.2017.09.018
- VernacularTitle:物质依赖的代谢组学研究进展
- Author:
Sufang PENG
1
;
Min ZHAO
Author Information
1. 上海交通大学医学院附属精神卫生中心物质依赖研究中心
- Keywords:
Metabonomics;
Drug dependence;
Research progress
- From:
Chinese Journal of Behavioral Medicine and Brain Science
2017;26(9):856-859
- CountryChina
- Language:Chinese
-
Abstract:
Drug dependence brings heavy burden to globe medicine and security,however,the mechanism is unclear.And because of the legal question,patients tend to hide their history of drug use,which make the diagnosis difficult.Metabonomics is an emerging system biological technology which can offer a new view about the diseases.This paper reviewed the metabonomics research progress of the main dependence drugs,and proved that metabonomics technology may discover biomarkers for diagnosis and treatment of drug dependence.The relationship between peripheral metabonomics and center nerve system may become an important research field.More information may come from the united apply of genomics,proteomics and metabonomics.Finally,there will be a breakthrough in identification of individuals with susceptibility to drug dependence,and supply a preventive or treatment plan.
