The value of preoperative NLR and PLR combined with the consensus in surgical decision making for branch duct intraductal papillary mucinous neoplasm of the pancreas
10.3760/cma.j.issn.1007-631X.2017.09.004
- VernacularTitle:术前NLR和PLR联合各共识在胰腺分支型导管内乳头状肿瘤手术决策中的价值
- Author:
Yadong XU
1
;
Lei ZHANG
;
Abulimiti NUERXIATI
;
Guochao ZHAO
;
Ning PU
;
Xuefeng XU
;
Dansong WANG
;
Tiantao KUANG
;
Wenhui LOU
;
Wenchuan WU
Author Information
1. 复旦大学附属中山医院普外科
- Keywords:
Pancreatic neoplasms;
Diagnosis;
NLR;
PLR
- From:
Chinese Journal of General Surgery
2017;32(9):733-737
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the difference among the 3 guidehnes used to make surgical decision for branch duct intraductal papillary mucinous neoplasm (BD-IPMN),then the guidelines were combined with neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) respectively for further analysis.Methods Clinical data of 51 appropriate BD-IPMN patients who underwent surgical resection from January 2008 to December 2015 was retrospectively analyzed.Results The significant difference was exist in the consensus for followup criterion (P ＜ 0.05).The preoperative NLR and PLR were helpful for the differential diagnosis between malignant and benign BD-IPMN,because the receiver operating characteristic curve (ROC) of NLR and PLR for prediction were 0.686 and 0.692,and the best boundary values were 2.64,92.56 respectively.The consensus combined with PLR could improve the specificity and positive predictive value (PPV),besides,the specificity and PPV could achieve 70.3％,54.2％ respectively while the sensitivity (92.9％) still remained at an ideal level after international consensus guideline combined with PLR.Conclusions NLR ≥ 2.64 and PLR ≥ 92.56 were predictive markers for the presence of BD-IPMN associated invasive tumor.The addition of PLR as a criterion to the international consensus guideline improved the accuracy of international consensus guidelines in estimating invasive BD-IPMN.
