Relationship between disease progression of primary gastric cancer and preoperative neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio
10.3969/j.issn.1009-9905.2017.07.008
- VernacularTitle:术前外周血NLR和PLR与原发性胃癌病程进展的关系
- Author:
wen Wen YU
1
,
2
;
yu Rui TAO
;
xu Kai YAN
;
tao Hong LI
;
peng Xiao HAN
;
bin Hong LIU
Author Information
1. 兰州军区兰州总医院普外科 甘肃 兰州 730050
2. 兰州大学第二临床医学院 甘肃 兰州 730000
- Keywords:
Gastric cancer;
Neutrophil-to-lymphocyte ratio;
Platelet-to-lymphocyte ratio;
Disease progression
- From:
Chinese Journal of Current Advances in General Surgery
2017;20(7):531-534
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate The relationship between the disease progression of primary gastric cancer and preoperative neutrophil-to-lymphocyte ratio、platelet-to-lymphocyte ratio.Methods:A retrospective analysis of the clinical data of 188 cases treated in our hospital from April 2015 to February 2015 with primary gastric cancer.according to the peripheral venous blood NLR、PLR,analyze the relationship of NLR、PLR with different tumor infiltration depth、lymph node staging and TNM staging with statistical methods.Results:There is statistically significance of NLR、PLR between different groups (P＜0.01);tumor infiltration depth,lymph node staging and TNM stage of high NLR、PLR group in patients with gastric cancer were higher than low NLR、PLR group,the difference is statistically significant (P＜0.01);NLR is significantly positive correlated to PLR (r=0.379,P＜0.001);Multiple linear regression analysis shows the above factors had significant effects on preoperative NLR,PLR (P＜0.05).Conclusions:Preoperative peripheral blood NLR and PLR levels may be value in predicting the progression of gastric cancer,High preoperative NLR indicates later disease progression and worse prognosis.
