Values of high-frequency ultrasound, elastography and ultrasound contrast in diagnosis of thyroid solid nodules
10.7687/j.issn1003-8868.2017.09.067
- VernacularTitle:高频超声、弹性成像及超声造影对甲状腺实性结节的诊断价值
- Author:
Ning SHANG
1
;
Hui DU
;
sheng Li GUO
;
Jun LI
;
Na SHI
;
yan Su ZHANG
;
gui Dou ZHAO
Author Information
1. 邯郸市传染病医院
- Keywords:
thyroid solid nodule;
high-frequency ultrasound;
elastography;
ultrasound contrast;
diagnosis;
distinguishing
- From:
Chinese Medical Equipment Journal
2017;38(9):67-70,77
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the diagnostic criteria of thyroid solid nodules by high-frequency ultrasound,elastography and ultrasound contrast.Methods Totally 87 patients with thyroid solid nodules underwent high-frequency ultrasound,elastography and ultrasound contrast before surgery,distinguishing benign from malignant lesions was executed based on pathological results,and according to the pathological character the image features by the three measures were compared.There were 40 patients divided into a control group going through the examination by high-frequency ultrasound,and 47 ones into an observation group with the examinations by the three measures.Pathological results were used as gold standard,and the two groups were compared on diagnostic sensitivity.Results High-frequency ultrasound showed significant differences of benign and malignant nodules in equal echo,very low echo,irregular peripheral halo,rates of clear nodule boundary and aspect ratio higher than as well as microcalcification (x2--4.603,17.394,5.833,14.832,10.107 and 27.392,and all Pvalues were less than 0.05).There were 85％ benign nodules gained grade Ⅰ and Ⅱ elastography images,81.82％malignant nodules had grade Ⅲ and ⅣV elastography images,and there were significant differences between benign and malignant nodules (x2=53.42,P=0.00).Ultrasound contrast found annular enhancement in most of benign nodules (x2=39.16,P＜0.01) while uneven enhancement in most of malignant nodules (x2=40.28,P＜0.01),and the nodule ranges increasedsignificantly after contrast (t=2.19,P＜0.05).The observation group had the sensitivity being 82.86％,which was statisticallyhigher than 59.38％ in the control group (x2=4.537,P--0.033).Conclusion High-frequency ultrasound,elastography and ultrasound contrast all show the manifestations of thyroid solid nodules,and the comprehensive application of the above three measures contributes to determining the nature of the nodules.
