Research advance of cognitive reserve in brain aging
10.7687/j.issn1003-8868.2017.09.093
- VernacularTitle:认知储备在大脑老化中的研究进展
- Author:
Lan LIN
1
;
wen Bai ZHANG
;
xuan Jing WANG
;
jian Hong GAO
;
cai Shui WU
Author Information
1. 北京工业大学生命科学与生物工程学院
- Keywords:
cognitive reserve;
brain reserve;
brain aging;
proxy indicator;
quantitative measurement;
AD
- From:
Chinese Medical Equipment Journal
2017;38(9):93-98
- CountryChina
- Language:Chinese
-
Abstract:
The current proxy indicators and quantitative strategy were summarized for cognitive reserve,the findings of cognitive reserve was discussed then in brain aging and Alzheimer's disease,and some future research directions were presented about cognitive reserve.The reserve of brain explains the disjunction between clinical symptoms and the degree of brain damage,whereby some people can tolerate more of age-related or Alzheimer's disease pathology than others and maintain brain function.The cognitive reserve hypothesis has been widely used in epidemiological and neuroimaging studies,but it lacks a unified quantitative indicator.The future research of cognitive reserve should be focused on the development of quantitative indicators that cover a variety of potential factors dynamically.
