Progress in mitoepigenetic regulation and Alzheimer disease
10.3969/j.issn.1000-4718.2017.10.030
- VernacularTitle:线粒体表观遗传调控与阿尔茨海默病的研究进展
- Author:
lu Lu HAI
1
;
ge Ying LI
;
Lai WANG
;
gong Shi ZHU
Author Information
1. 河南大学生命科学学院
- Keywords:
Mitoepigenetic regulation;
Alzheimer disease;
Mitochondrial genome
- From:
Chinese Journal of Pathophysiology
2017;33(10):1912-1916
- CountryChina
- Language:Chinese
-
Abstract:
Mitochondrion is an organelle containing its own genome in eukaryotic cells , which encodes 37 genes involved in mitochondrial functions .Mitoepigenetic regulation is a major form of mitochondrial genome-encoded genes that regulates the expression levels without altering the sequences of the genes .The mitoepigenetic regulation is involved in the occurrence and development of various diseases .This paper reviews the progress of mitoepigenetic regulation and Alzhe-imer disease.