Clinical study on treatment of primary attack of knee osteoarthritis with bushen Huoxuetongluo decoction
10.3969/j.issn.1005-1678.2017.10.026
- VernacularTitle:补肾活血通络方加减辨治原发性膝骨性关节炎急性发作的临床研究
- Author:
qiang Jian CHEN
1
;
fang Xiao ZHANG
Author Information
1. 浙江省荣军医院
- Keywords:
Bushen Huoxue Tongluo recipe;
primary osteoarthritis of the knee;
acute attack;
curative effect
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(10):66-68
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical effect of Bushen Huoxue Tongluo Recipe in the treatment of acute attack of primary knee osteoarthritis, so as to enrich the treatment method and improve the curative effect. Methods 94 cases of primary knee osteoarthritis acute attack were randomly divided into 2 groups, 47 cases in the control group were treated with conventional western medicine treatment, the observation group of 47 cases, treated with Bushen Huoxue Tongluo Decoction, were observed after treatment in the improvement of the safety index, serum indexes and related score. Results The two groups at the end of the pain, stiffness, ADL, tenderness, swelling, joint activities are significantly lower than before treatment, after treatment were significantly different (P<0.05) at the end of treatment, the observation group in the above six indicators were significantly better than the control group (P<0.05); group MMP-3, two at the end of treatment CRP, IL-1, TNF- were significantly lower than before treatment, after treatment were significantly different (P<0.05) at the end of treatment observation group above index was significantly better than the control group (P<0.05). Conclusion: Bushen Huoxue Tongluo Decoction can improve the primary acute exacerbation of knee osteoarthritis clinical symptoms, reduce inflammation, and high safety.