Clinical efficacy of zoledronic acid in the treatment of osteoporotic unstable intertrochanteric fracture in the elderly
10.3969/j.issn.1005-1678.2017.10.033
- VernacularTitle:唑来膦酸治疗高龄骨质疏松性不稳定转子间骨折患者的临床效果观察
- Author:
ming Shu HUANG
1
;
hua Shu LAN
;
lin Hai XING
Author Information
1. 丽水市中心医院 创伤骨科
- Keywords:
zoledronic acid;
osteoporotic unstable intertrochanteric fracture;
advanced age
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(10):83-84
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study and analyze the clinical efficacy of zoledronic acid in the treatment of osteoporotic intertrochanteric fracture in elderly patients. Methods 100 elderly patients with osteoporotic unstable intertrochanteric fracture treated in our hospital from February 2014 to July 2016 were selected and randomly divided into the control group and the experimental group. There were 50 patients in each group. The control group received routine treatment (calcitonin), and the experimental group was treated with zoledronic acid.The clinical indicators of the two groups were compared and analyzed. Results After the corresponding treatment, the VAS scores of the experimental group and the control group were (0.36±0.42) and (0.34±0.40), and there was no statistical significance. The excellent rate of hip joint function was 82% in the control group, and the excellent and good rate of hip joint function in the experimental group was 80%, which was not statistically significant. In addition, there were no statistically significant differences in fracture healing time and complications between the two groups. After 1 years, the hip bone mineral density and the lumbar vertebral bone mineral density were (0.78±0.05) g/cm2, and (0.85±0.06) g/cm2 were significantly higher than those in the control group,with statistical significance (P<0.05). Conclusion Zoledronic acid in the treatment of senile osteoporotic unstable intertrochanteric fracture clinical effect is remarkable,can increase bone mineral density in a large extent, the joint recovery had no effect, has clinical significance.
