Radiation Dose from Whole-Body F-18 Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography: Nationwide Survey in Korea.
10.3346/jkms.2016.31.S1.S69
- Author:
Hyun Woo KWON
1
;
Jong Phil KIM
;
Hong Jae LEE
;
Jin Chul PAENG
;
Jae Sung LEE
;
Gi Jeong CHEON
;
Dong Soo LEE
;
June Key CHUNG
;
Keon Wook KANG
Author Information
1. Department of Nuclear Medicine, Seoul National University Hospital, Seoul, Korea. paengjc@snu.ac.kr
- Publication Type:Original Article ; Research Support, Non-U.S. Gov't
- Keywords:
FDG PET/CT;
Radiation Exposure;
National Survey;
Dose Reference Level
- MeSH:
Child;
Child, Preschool;
Fluorodeoxyglucose F18/chemistry;
Humans;
Infant;
*Positron-Emission Tomography;
*Radiation Dosage;
Surveys and Questionnaires;
*Tomography, X-Ray Computed;
*Whole Body Imaging
- From:Journal of Korean Medical Science
2016;31(Suppl 1):S69-S74
- CountryRepublic of Korea
- Language:English
-
Abstract:
The purpose of this study was to estimate average radiation exposure from 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) examinations and to analyze possible factors affecting the radiation dose. A nation-wide questionnaire survey was conducted involving all institutions that operate PET/CT scanners in Korea. From the response, radiation doses from injected FDG and CT examination were calculated. A total of 105 PET/CT scanners in 73 institutions were included in the analysis (response rate of 62.4%). The average FDG injected activity was 310 +/- 77 MBq and 5.11 +/- 1.19 MBq/kg. The average effective dose from FDG was estimated to be 5.89 +/- 1.46 mSv. The average CT dose index and dose-length product were 4.60 +/- 2.47 mGy and 429.2 +/- 227.6 mGycm, which corresponded to 6.26 +/- 3.06 mSv. The radiation doses from FDG and CT were significantly lower in case of newer scanners than older ones (P < 0.001). Advanced PET technologies such as time-of-flight acquisition and point-spread function recovery were also related to low radiation dose (P < 0.001). In conclusion, the average radiation dose from FDG PET/CT is estimated to be 12.2 mSv. The radiation dose from FDG PET/CT is reduced with more recent scanners equipped with image-enhancing algorithms.
