Effect of Qixie Huoxue Tongluo decoction combined with ozagrel in treatment of cerebral thrombosis and cerebral ischemia reperfusion injury
10.3969/j.issn.1005-1678.2017.10.060
- VernacularTitle:芪蝎活血通络汤联合奥扎格雷钠治疗脑血栓形成及改善脑缺血再灌注损伤的效果分析
- Author:
hong Wan ZHANG
1
Author Information
1. 千阳县人民医院 神经内科
- Keywords:
Qingxiehuoxue Huoxue Tongluo decoction;
ozagrel sodium;
cerebral thrombosis;
cerebral ischemia-reperfusion injury
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(10):150-152
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect of Qixuoxue Huoxue Tongluo decoction combined with ozagrel sodium on cerebral thrombosis and to improve cerebral ischemia-reperfusion injury. Methods 106 patients of cerebral thrombosis from April 2015 to April 2016 were divided into control group and observation group, each group of 53 patients. The patients in the control group were treated with ozagrel sodium for reperfusion. The observation group was treated with Qixiqi Huoxue Tongluo decoction and ozagrel sodium for treatment. Resulrs The levels of inflammatory factors (hs-CRP, TNF-α, etc.) in the observation group were lower than those in the observation group (P<0.05), and the two groups were compared with the observation group (P<0.05). The adverse effects of NIHSS and ADL were higher than those of the control group (P<0.05). The adverse effects of NIHSS and ADL were significantly lower than those of the control group (P<0.05) ; Conclusion Qixie Huoxue Tongluo Decoction combined with ozagrel sodium for cerebral thrombosis patients have a good therapeutic effect, for cerebral ischemia and reperfusion injury also have some improvement.