Comparative observation of Methylprednisolone and gamma globulin in the treatment of acute myelitis
10.3969/j.issn.1005-1678.2017.10.065
- VernacularTitle:甲基强的松龙与丙种球蛋白联合治疗急性脊髓炎的对比观察
- Author:
Juan LI
1
;
Jun ZHOU
;
qin Shu ZHAN
Author Information
1. 西安交通大学第二附属医院 神经内科
- Keywords:
Methylprednisolone;
acute myelitis;
gamma globulin;
clinical efficacy
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(10):163-164
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study and analyze the efficacy of Methylprednisolone and gamma globulin in the treatment of acute myelitis. Methods 100 cases of acute myelitis in the second affiliated hospital of Xi'an Jiaotong University were selected as the research objects, and the control group was treated with Dexamethasone. The experimental group was treated with Methylprednisolone combined with gamma globulin. The clinical efficacy, adverse reactions and related clinical indicators of the experimental group and the control group were compared and analyzed. Results The effective rate of the experimental group (92.0 %) was significantly better than (82.0 %) of the control group with statistical difference (P<0.05). There were no obvious adverse reactions in the two groups, the incidence rate was 8.0% and 10.0 % respectively, and there was no significant difference. Time of muscle strength improved two level in the control group (18.90±5.23) d was significantly longer than that (10.87±4.30) d of the experimental group, the experimental group hospitalization time, sensory recovery time and recovery of urinary function and other indicators are better than the control group, with statistical difference (P<0.05). Conclusion Methylprednisolone combined with gamma globulin in the treatment of acute myelitis has ideal efficacy, could significantly improve the patient's muscle strength with high safety.
