Observation on the efficacy and safety of Gukang capsule combinedwithsodium hyaluronate injection on the treatment of the patients with osteoarthritis
10.3969/j.issn.1005-1678.2017.10.070
- VernacularTitle:骨康胶囊联合透明质酸钠局部注射治疗骨性关节炎的疗效及安全性
- Author:
jian Xin LV
1
;
zhong Xiao YU
;
chuan Ji LI
;
qi Peng LV
;
Feng XIANG
Author Information
1. 永康市骨科医院 骨科
- Keywords:
osteoarthritis;
Gukang capsule;
sodium hyaluronate;
safety
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(10):173-174
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect and safety of Gukang capsule combined with sodium hyaluronate injection on the treatment of the patients with osteoarthritis. Methods 94 osteoarthritis patients selected from December 2015 to March 2017 were randomly divided into study group (n=47) and control group (n=47). The control group were given sodium hyaluronate injection, the study group were received local injection of sodium hyaluronate combined with Gukang capsule. The changes of knee joint function (HSS scale score) and adverse reaction rate were recorded and compared before and after treatment in the two groups. Results Before treatment, there was no significant difference in HSS scores between the two groups. After treatment, the HSS score in the study group was significantly better than that in the control group (P<0.05). There were no significant differences in the adverse reactions between the 2 groups during the treatment. Conclusion Local injection of sodium hyaluronate combined with Gukang capsule on the treatment of osteoarthritis, which can significantly improve the clinical efficacy, the security is higher. .