Progress of research on the treatment of diabetic nephropathy with renin angiotensin aldosterone inhibitors
10.3969/j.issn.1005-1678.2017.10.201
- VernacularTitle:肾素-血管紧张素-醛固酮抑制剂治疗糖尿病肾病的研究进展分析
- Author:
Xuan HU
1
;
lin lin WANG
Author Information
1. 天津华兴医院 内科
- Keywords:
renin-angiotensin-aldosterone inhibitor;
diabetic nephropathy
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(10):456-458
- CountryChina
- Language:Chinese
-
Abstract:
Diabetes is one of the most common clinical chronic diseases, the incidence can lead to a variety of complications, diabetic nephropathy is one of them, because the incidence of diabetes is increasing year by year, so the incidence of diabetic nephropathy also gradually upgrade. The activation of the renin-angiotensin-aldosterone system (RAAS) is important in the occurrence and progression of the disease. RAAS inhibitors have a good control over the patient's blood pressure and can also be reduced in urinary protein small ball high filtration degree decreased, its renal interstitial fibrosis also has a certain inhibitory effect. The study showed that the RAAS inhibitor slowed the progression of the disease, the incidence of end-stage renal disease decreased significantly. This article will elaborate and analyze the progress of the application of RAAS inhibitors in the treatment of diabetic nephropathy to help more researchers enhance their understanding and improve the clinical efficacy of diabetic nephropathy.