Clinical analysis of ligustrazine in the treatment of chronic renal failure

VernacularTitle:川芎嗪治疗慢性肾功能衰竭患者的临床分析
Author: wei Zi CHEN ¹ ; Wei ZHANG
Author Information

1. 台州市中心医院肾内科
Keywords: chronic renal failure; ligustrazine
From: Chinese Journal of Biochemical Pharmaceutics 2017;37(10):223-224
CountryChina
Language:Chinese
Abstract: Objective To investigate the clinical effect of ligustrazine on the treatment of chronic renal failure. Methods 94 patients with chronic renal failure from Oct. 2015 to Jan. 2017 of Taizhou central hospital were randomly divided into two groups: the study group (n=47) and the control group (n=47), the control group were received routine clinical treatment, the study group were treated with ligustrazine on the basis of routine treatment. Scr, Ccr, BUN and adverse reaction in the two groups were recorded and compared. Results Scr, Ccr, BUN between the two groups has no statistically difference. After treatment, Scr, Ccr and BUN in the study group were better than those in the control group (P<0.05). There was no significant difference in adverse reactions between the two groups. Conclusion On the basis of routine drug treatment, ligustrazine can significantly improve the clinical efficacy of patients with chronic renal failure, and less adverse reactions.