To purify Japanese encaphalitis virus for vaccine production at semiindustrial scale
- Author:
Doan Thi Thuy
- Publication Type:Journal Article
- Keywords:
Japanese encaphalitis virus
- MeSH:
Encephalitis, Japanese;
Encephalitis Virus, Japanese;
Viruses;
Vaccines
- From:Journal of Practical Medicine
2003;445(3):19-20
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
42 lots of Japaness encaphalitis virus were purified from viral infected rat brain mixture, for obtaining 28 lots of vaccine products. All lots of vaccine were met WHO standard through local and national laboratory qualification ultracentrifugal 126000 g within 5 hours demonstrated that saturated ammonium sulphate precipitated procedure had removed 26.4% to 32% of protein, then ultricentyrifugal sucrose had removed almost the rest. Protein contents in producted vaccine reached 6.53-61.3%
