Gender Differences for Long-term Prognosis in Patients With Chronic Heart Failure
10.3969/j.issn.1000-3614.2017.10.004
- VernacularTitle:慢性心功能不全患者长期预后的性别差异
- Author:
Yan YAN
1
;
tong Tong YU
;
qing Zhao SUN
;
jun Zhi SUN
Author Information
1. 中国医科大学附属盛京医院 心内科
- Keywords:
Heart failure;
Prognosis;
Gender factor
- From:
Chinese Circulation Journal
2017;32(10):948-951
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To analyze gender differences for the long-term prognosis in patients with chronic heart failure (CHF). Methods: A total of 925 consecutive CHF patients admitted in our hospital were enrolled those including 460 (49.7%) female. The mean follow-up time was 3.4 years and the end point event was all-cause mortality. Gender differences for the long-term prognosis in CHF patients were studied by Cox proportional-hazards regression analysis. Results: The overall all-cause mortality was 27.9% during follow-up period, mortality in female was 25.2% and in male was 30.5%. Multivariate Cox regression analysis presented that the long-term death risk in male patients was higher than female (HR=1.309, 95% CI 1.002-1.708, P=0.048). Subgroup analysis showed that for patients age≥65 years, LVEF<45%and with NYHA grade III/IV, the long-term prognosis in female was much better than male. Conclusion: Long-term prognosis of CHF in female patients was better than male; female at age≥65 years, LVEF<45%and NYHA grade III/IV had the better prognosis.