Ribosomal proteins and tumors
10.3760/cma.j.issn.1673-422X.2017.08.007
- VernacularTitle:核糖体蛋白与肿瘤
- Author:
Xingya RUAN
1
;
Mingxia YANG
Author Information
1. 南京医科大学附属常州市第二人民医院呼吸科常州市第二人民医院心肺血管研究所
- Keywords:
Neoplasms;
Ribosomal proteins
- From:
Journal of International Oncology
2017;44(8):587-589
- CountryChina
- Language:Chinese
-
Abstract:
The ribosome composed of ribosomal RNA and ribosomal proteins is well documented to be an important organelle for protein synthesis.Ribosomal proteins play crucial roles in protein translation.The dysregulation of ribosomal proteins and ribosomal RNA expression activates ribosomal proteins' extraribosomal functions which is believed to play important roles in the tumorigenesis.It is possible that ribosomal proteins may serve as biomarkers or promising targets for the early diagonosis and therapy of tumor diseases.
