Analysis of intra-tumor heterogeneity in breast cancer precision medicine
10.3760/cma.j.issn.1673-422X.2017.08.012
- VernacularTitle:瘤内异质性分析指导乳腺癌精准医疗
- Author:
Zongbi YI
1
;
Fei MA
Author Information
1. 100021,国家癌症中心中国医学科学院北京协和医学院肿瘤医院肿瘤内科
- Keywords:
Breast neoplasms;
Intra-tumor heterogeneity;
Precision medicine
- From:
Journal of International Oncology
2017;44(8):604-607
- CountryChina
- Language:Chinese
-
Abstract:
As a breakthrough of precision medicine,intra-tumor heterogeneity is a research hotspot and is correlated to tumorigenesis,metastasis and resistance to therapies.In breast cancer,evidence of intra-tumor heterogeneity has been documented by numerous studies and it is the main obstacle to find ideal tumor markers and personalized medicine.Further analysis including the feature and generation mechanism of intra-tumor heterogeneity and the methods to assessment intra-tumor heterogeneity in the clinic are the key to cancer precision medicine.
