Efficacy and safety of intravenous thrombolysis in hyperglycemic patients with minor stroke
10.3969/j.issn.1006-5725.2017.20.029
- VernacularTitle:小卒中合并高血糖患者静脉溶栓的有效性和安全性
- Author:
Hong CHANG
1
;
Yanxiang LI
;
Lin WANG
Author Information
1. 300400,天津市北辰医院
- Keywords:
minor stroke;
hyperglycemia;
rt-PA;
intravenous thrombolysis
- From:
The Journal of Practical Medicine
2017;33(20):3444-3448
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the efficacy and safety of thrombolysis therapy for hyperglycemic patients suffering from minor stroke. Methods Intravenous thrombolysis by rtPA was given to hyperglycemic patients suffering from minor stroke. The recovery of neurological deficits and other clinical parameters were recorded 24 hours ,7 days and 90 days after treatment in randomized thrombolytic group and non-thrombolytic group. Results Neurological recovery rate of minor stroke patients with diabetes in thrombolytic group was higher than that in non-thrombolytic group 24 hours,7 days and 90 days after the treatment(P < 0.05)and the incidence of aggravation or worsening of clinical symptoms in thrombolytic group was lower than that of non-thrombolytic group(P < 0.05). There was no significant difference in the recovery rate of neurological deficits and the incidence of exacerbation or deterioration of clinical symptoms in hyperglycemic patients suffering from minor stroke. No intra-cranial hemorrhage occurred in both groups. Conclusion It is of great significance for minor stroke patients with diabetes to receive intravenous thrombolysis ,which is a safer clinical alternative.
