Study on Extraction and Inclusion Process of Volatile Oil from Citri Grandis Exocarpium with Saturated Aqueous Solution
10.3969/j.issn.1005-5304.2017.11.016
- VernacularTitle:化橘红药材挥发油提取及用饱和水溶液法包合工艺研究
- Author:
ping Wen WANG
1
;
bin Xing YIN
;
xu Xiao DONG
;
jing Chun YANG
;
ying Hai ZHANG
;
tai Long YOU
;
Jian NI
Author Information
1. 北京中医药大学中药学院
- Keywords:
Citri Grandis Exocarpium;
volatile oil;
extraction;
β-CD;
inclusion process
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2017;24(11):67-70
- CountryChina
- Language:Chinese
-
Abstract:
Objective To optimize the processes of extraction and inclusion of volatile oil from Citri Grandis Exocarpium. Methods With yield ratio of volatile oil as evaluation index, single factor experiments were used to study the extraction process of volatile oil. With the inclusion rate of the volatile oil and the yield of inclusion as evaluation indexes, saturated aqueous solution was used to the L9(34) orthogonal experiments to reach the best inclusion process optimization. And the microscopic imaging analysis and X-ray scattering technology were adopted to character the inclusion compound. Results The optimum extraction process of volatile oil was extracted for 10 hours with 10 folds the amount of water, and without soaking. The optimum conditions of inclusion process were as follows: volatile oil (mL): β-CD (g): water (mL) ratio was 1:8:80; inclusion temperature was 50 ℃; inclusion time was 3 hour. The validation experiments of the inclusion rate of the volatile oil and the yield of inclusion were 91.50% and 88.36%. Microscopic imaging analysis and X-ray scattering technology proved the inclusion compound had been formed. Conclusion Optimal extraction and inclusion process are feasible and stable, which can provide certain supporting data for preparation and production.
